Intra-Domain Residue Coevolution in Transcription Factors Contributes to DNA Binding Specificity

Understanding the basis of the DNA-binding specificity of transcription factors (TFs) has been of long-standing interest. Despite extensive efforts to map millions of putative TF binding sequences, identifying the critical determinants for DNA binding specificity remains a major challenge. The coevo...

Descripción completa

Detalles Bibliográficos
Autores principales: Luan, Yizhao, Tang, Zehua, He, Yao, Xie, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100741/
https://www.ncbi.nlm.nih.gov/pubmed/36943132
http://dx.doi.org/10.1128/spectrum.03651-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100741/
https://www.ncbi.nlm.nih.gov/pubmed/36943132
http://dx.doi.org/10.1128/spectrum.03651-22

Ejemplares similares