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Intra-Domain Residue Coevolution in Transcription Factors Contributes to DNA Binding Specificity
Understanding the basis of the DNA-binding specificity of transcription factors (TFs) has been of long-standing interest. Despite extensive efforts to map millions of putative TF binding sequences, identifying the critical determinants for DNA binding specificity remains a major challenge. The coevo...
Autores principales: | Luan, Yizhao, Tang, Zehua, He, Yao, Xie, Zhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100741/ https://www.ncbi.nlm.nih.gov/pubmed/36943132 http://dx.doi.org/10.1128/spectrum.03651-22 |
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