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Global Metabolomic Profiling of Host Red Blood Cells Infected with Babesia divergens Reveals Novel Antiparasitic Target Pathways

Babesia divergens is an apicomplexan parasite that infects human red blood cells (RBCs), initiating cycles of invasion, replication, and egress, resulting in extensive metabolic modification of the host cells. Babesia is an auxotroph for most of the nutrients required to sustain these cycles. There...

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Detalles Bibliográficos
Autores principales: Beri, Divya, Singh, Manpreet, Rodriguez, Marilis, Goyal, Naman, Rasquinha, Giselle, Liu, Yunfeng, An, Xiuli, Yazdanbakhsh, Karina, Lobo, Cheryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100774/
https://www.ncbi.nlm.nih.gov/pubmed/36786651
http://dx.doi.org/10.1128/spectrum.04688-22