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Host-Erythrocytic Sphingosine-1-Phosphate Regulates Plasmodium Histone Deacetylase Activity and Exhibits Epigenetic Control over Cell Death and Differentiation

The evolution of resistance to practically all antimalarial drugs poses a challenge to the current malaria elimination and eradication efforts. Given that the epigenome of Plasmodium falciparum governs several crucial parasite functions, pharmaceutical interventions with transmission-blocking potent...

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Detalles Bibliográficos
Autores principales: Sah, Raj Kumar, Anand, Sakshi, Dar, Waseem, Jain, Ravi, Kumari, Geeta, Madan, Evanka, Saini, Monika, Gupta, Aashima, Joshi, Nishant, Hada, Rahul Singh, Gupta, Nutan, Pati, Soumya, Singh, Shailja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100792/
https://www.ncbi.nlm.nih.gov/pubmed/36744922
http://dx.doi.org/10.1128/spectrum.02766-22