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Porcine Epidemic Diarrhea Virus nsp7 Inhibits MDA5 Dephosphorylation to Antagonize Type I Interferon Production

Porcine epidemic diarrhea virus (PEDV) is a reemerging enteropathogenic coronavirus that causes high mortality in piglets and has catastrophic effects on the global pig industry. PEDV-encoded nonstructural protein 7 (nsp7) is an important component of the viral replication and transcription complex,...

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Detalles Bibliográficos
Autores principales: Zhang, Jiansong, Fang, Puxian, Ren, Jie, Xia, Sijin, Zhang, Huichang, Zhu, Xuerui, Ding, Tong, Xiao, Shaobo, Fang, Liurong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100820/
https://www.ncbi.nlm.nih.gov/pubmed/36975829
http://dx.doi.org/10.1128/spectrum.05017-22