Cargando…

Effects of Lumacaftor-Ivacaftor on Airway Microbiota-Mycobiota and Inflammation in Patients with Cystic Fibrosis Appear To Be Linked to Pseudomonas aeruginosa Chronic Colonization

Lumacaftor-ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator combination approved for patients with cystic fibrosis (CF) who are homozygous for the F508del allele. This treatment showed significant clinical improvement; however, few studies have addressed the evolut...

Descripción completa

Detalles Bibliográficos
Autores principales: Enaud, Raphael, Lussac-Sorton, Florian, Charpentier, Elena, Velo-Suárez, Lourdes, Guiraud, Jennifer, Bui, Stéphanie, Fayon, Michael, Schaeverbeke, Thierry, Nikolski, Macha, Burgel, Pierre-Régis, Héry-Arnaud, Geneviève, Delhaes, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100832/
https://www.ncbi.nlm.nih.gov/pubmed/36971560
http://dx.doi.org/10.1128/spectrum.02251-22