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Effects of Lumacaftor-Ivacaftor on Airway Microbiota-Mycobiota and Inflammation in Patients with Cystic Fibrosis Appear To Be Linked to Pseudomonas aeruginosa Chronic Colonization
Lumacaftor-ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator combination approved for patients with cystic fibrosis (CF) who are homozygous for the F508del allele. This treatment showed significant clinical improvement; however, few studies have addressed the evolut...
Autores principales: | Enaud, Raphael, Lussac-Sorton, Florian, Charpentier, Elena, Velo-Suárez, Lourdes, Guiraud, Jennifer, Bui, Stéphanie, Fayon, Michael, Schaeverbeke, Thierry, Nikolski, Macha, Burgel, Pierre-Régis, Héry-Arnaud, Geneviève, Delhaes, Laurence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100832/ https://www.ncbi.nlm.nih.gov/pubmed/36971560 http://dx.doi.org/10.1128/spectrum.02251-22 |
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