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A Rapid Method for Generating Infectious SARS-CoV-2 and Variants Using Mutagenesis and Circular Polymerase Extension Cloning

The appearance of SARS-CoV-2 variants in late 2020 raised alarming global public health concerns. Despite continued scientific progress, the genetic profiles of these variants bring changes in viral properties that threaten vaccine efficacy. Thus, it is critically important to investigate the biolog...

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Detalles Bibliográficos
Autores principales: Kim, Beom Kyu, Choi, Won-Suk, Jeong, Ju Hwan, Oh, Sol, Park, Ji-Hyun, Yun, Yu Soo, Min, Seong Cheol, Kang, Da Hyeon, Kim, Eung-Gook, Ryu, Hojin, Kim, Hye Kwon, Baek, Yun Hee, Choi, Young Ki, Song, Min-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100849/
https://www.ncbi.nlm.nih.gov/pubmed/36877070
http://dx.doi.org/10.1128/spectrum.03385-22