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Mitofusin 1-Mediated Redistribution of Mitochondrial Antiviral Signaling Protein Promotes Type 1 Interferon Response in Human Cytomegalovirus Infection

One of the most potent anti-human cytomegalovirus (HCMV) immune mechanisms possessed by host cells is type I interferon (IFN1), which induces the expression of IFN-stimulated genes (ISGs). During this process, mitochondria play an important role in the IFN1 response, and mitofusin 1 (MFN1) is a key...

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Detalles Bibliográficos
Autores principales: Huang, Kaizhao, Pei, Shunjie, Sun, Yi, Xu, Xi, Fang, Yangyang, Lai, Meimei, Xiang, Guangxin, Xu, Feng, Zheng, Xiaoqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100850/
https://www.ncbi.nlm.nih.gov/pubmed/36939338
http://dx.doi.org/10.1128/spectrum.04615-22