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Oral Administration of Universal Bacterium-Vectored Nucleocapsid-Expressing COVID-19 Vaccine is Efficacious in Hamsters

Oral delivery of an inexpensive COVID-19 (coronavirus disease 2019) vaccine could dramatically improve immunization rates, especially in low- and middle-income countries. Previously, we described a potential universal COVID-19 vaccine, rLVS ΔcapB/MN, comprising a replicating bacterial vector, LVS (l...

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Detalles Bibliográficos
Autores principales: Jia, Qingmei, Bielefeldt-Ohmann, Helle, Maison, Rachel M., Hartwig, Airn, Masleša-Galić, Saša, Bowen, Richard A., Horwitz, Marcus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100875/
https://www.ncbi.nlm.nih.gov/pubmed/36916971
http://dx.doi.org/10.1128/spectrum.05035-22