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In Vitro Activity of Two Cefepime-Based Novel Combinations, Cefepime/Taniborbactam and Cefepime/Zidebactam, against Carbapenemase-Expressing Enterobacterales Collected in India

In recent times, discovery efforts for novel antibiotics have mostly targeted carbapenemase-producing Gram-negative organisms. Two different combination approaches are pertinent: β-lactam–β-lactamase inhibitor (BL/BLI) or β-lactam–β-lactam enhancer (BL/BLE). Cefepime combined with a BLI, taniborbact...

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Detalles Bibliográficos
Autores principales: Bakthavatchalam, Yamuna Devi, Elangovan, Divyaa, Jaganathan, Subha Vajjiravelu, Subburaju, Nivedhana, Shankar, Abirami, Manokaran, Yuvasri, J., Sudarsana, Devi, Rema, Baveja, Sujata, Devi, Sheela, S., Jayakumar, Bhattacharya, Sanjay, S. M., Rudresh, Yesudhason, Bineshlal, Shetty, Vignesh, Mutreja, Ankur, Manesh, Abi, Varghese, George M., Marwick, Charis A., Parcell, Benjamin J., Gilbert, Ian H., Veeraraghavan, Balaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100882/
https://www.ncbi.nlm.nih.gov/pubmed/36847537
http://dx.doi.org/10.1128/spectrum.04925-22