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Antifungal Peptide SP1 Damages Polysaccharide Capsule of Cryptococcus neoformans and Enhances Phagocytosis of Macrophages

Cryptococcus neoformans is a fungal pathogen which causes nearly half a million deaths worldwide each year. Under host-relevant conditions, it produces a characteristic polysaccharide capsule. The polysaccharide capsule is one of the main virulence factors of C. neoformans, which involves antiphagoc...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Zhang, Yang, Zhao, Xi, Lu, Weilai, Zhong, Yuxin, Fu, Yu V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100895/
https://www.ncbi.nlm.nih.gov/pubmed/36916981
http://dx.doi.org/10.1128/spectrum.04562-22