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Synergy between Genome Mining, Metabolomics, and Bioinformatics Uncovers Antibacterial Chlorinated Carbazole Alkaloids and Their Biosynthetic Gene Cluster from Streptomyces tubbatahanensis sp. nov., a Novel Actinomycete Isolated from Sulu Sea, Philippines

In this study, a novel actinomycete strain, DSD3025(T), isolated from the underexplored marine sediments in Tubbataha Reefs Natural Park, Sulu Sea, Philippines, with the proposed name Streptomyces tubbatahanensis sp. nov., was described using polyphasic approaches and characterized using whole-genom...

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Detalles Bibliográficos
Autores principales: Tenebro, Chuckcris P., Trono, Dana Joanne V. L., Balida, Lex Aliko P., Bayog, Leah Katrine A., Bruna, Julyanna R., Sabido, Edna M., Caspe, Dion Paul C., de Los Santos, Emmanuel Lorenzo C., Saludes, Jonel P., Dalisay, Doralyn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100901/
https://www.ncbi.nlm.nih.gov/pubmed/36809153
http://dx.doi.org/10.1128/spectrum.03661-22