The Lysin Exebacase Has a Low Propensity for Resistance Development in Staphylococcus aureus and Suppresses the Emergence of Resistance to Antistaphylococcal Antibiotics

Exebacase (CF-301) belongs to a novel class of protein-based antibacterial agents, called lysins (peptidoglycan hydrolases). Exebacase exhibits potent antistaphylococcal activity and is the first lysin to initiate clinical trials in the United States. To support clinical development, the potential f...

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Detalles Bibliográficos
Autores principales: Oh, Jun, Warner, Matthew, Ambler, Jane E., Schuch, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100934/
https://www.ncbi.nlm.nih.gov/pubmed/36862002
http://dx.doi.org/10.1128/spectrum.05261-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100934/
https://www.ncbi.nlm.nih.gov/pubmed/36862002
http://dx.doi.org/10.1128/spectrum.05261-22

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