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Exposure to Secreted Bacterial Factors Promotes HIV-1 Replication in CD4(+) T Cells

Microbial translocation is associated with systemic immune activation in HIV-1 disease. Circulating T cells can encounter microbial products in the bloodstream and lymph nodes, where viral replication takes place. The mechanisms by which bacteria contribute to HIV-associated pathogenesis are not com...

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Detalles Bibliográficos
Autores principales: Znaidia, M., de Souza-Angelo, Y., Létoffé, S., Staropoli, I., Grzelak, L., Ghigo, J. M., Schwartz, O., Casartelli, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100953/
https://www.ncbi.nlm.nih.gov/pubmed/36853052
http://dx.doi.org/10.1128/spectrum.04313-22