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Excision of Integrated Human Herpesvirus 6A Genomes Using CRISPR/Cas9 Technology

Human herpesviruses 6A and 6B are betaherpesviruses that can integrate their genomes into the telomeres of latently infected cells. Integration can also occur in germ cells, resulting in individuals who harbor the integrated virus in every cell of their body and can pass it on to their offspring. Th...

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Detalles Bibliográficos
Autores principales: Aimola, Giulia, Wight, Darren J., Flamand, Louis, Kaufer, Benedikt B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100985/
https://www.ncbi.nlm.nih.gov/pubmed/36926973
http://dx.doi.org/10.1128/spectrum.00764-23