Development of a Heat-Killed fbp1 Mutant Strain as a Therapeutic Agent To Treat Invasive Cryptococcus Infection

In previous studies, we determined that the F-box protein Fbp1, a subunit of the SCF(Fbp1) E3 ligase in Cryptococcus neoformans, is essential for fungal pathogenesis. Heat-killed fbp1Δ cells (HK-fbp1) can confer vaccine-induced immunity against lethal challenge with clinically important invasive fun...

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Detalles Bibliográficos
Autores principales: Wang, Yina, Wang, Keyi, Rivera, Amariliz, Xue, Chaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101017/
https://www.ncbi.nlm.nih.gov/pubmed/36719231
http://dx.doi.org/10.1128/spectrum.04955-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101017/
https://www.ncbi.nlm.nih.gov/pubmed/36719231
http://dx.doi.org/10.1128/spectrum.04955-22

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