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Additive Therapy of Plasmodium berghei-Induced Experimental Cerebral Malaria via Dihydroartemisinin Combined with Rapamycin and Atorvastatin

Cerebral malaria (CM), caused by Plasmodium falciparum, is the primary cause of death from severe malaria. Even after immediate parenteral therapy with antimalarial drugs, the mortality rate remains 15 to 25%. Currently, no effective therapeutic agents are available for the radical treatment of CM....

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Detalles Bibliográficos
Autores principales: Song, Xiaonan, Cheng, Weijia, Zhu, Huiyin, Li, Yuting, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101104/
https://www.ncbi.nlm.nih.gov/pubmed/36946739
http://dx.doi.org/10.1128/spectrum.02317-22