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Linked Mutations in the Ebola Virus Polymerase Are Associated with Organ Specific Phenotypes

Ebola virus (EBOV) causes a severe infection called Ebola virus disease (EVD). The pathogenesis of EBOV infection is complex, and outcome has been associated with a variety of immunological and cellular factors. Disease can result from several mechanisms, including direct organ and endothelial cell...

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Detalles Bibliográficos
Autores principales: Dong, Xiaofeng, Tree, Julia, Banadyga, Logan, He, Shihua, Zhu, Wenjun, Tipton, Tom, Gouriet, Jade, Qiu, Xiangguo, Elmore, Michael J., Hall, Yper, Carroll, Miles, Hiscox, Julian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101120/
https://www.ncbi.nlm.nih.gov/pubmed/36946725
http://dx.doi.org/10.1128/spectrum.04154-22