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Glycopeptidolipid Defects Leading to Rough Morphotypes of Mycobacterium abscessus Do Not Confer Clinical Antibiotic Resistance

Mycobacterium abscessus is an emerging pathogen causing severe pulmonary infections. Within chronically infected patients, M. abscessus isolates undergo molecular changes leading to increased virulence and antibiotic resistance. Specifically, mutations in glycopeptidolipid (GPL) synthesis genes, lea...

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Detalles Bibliográficos
Autores principales: Hershko, Yizhak, Adler, Amos, Barkan, Daniel, Meir, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101123/
https://www.ncbi.nlm.nih.gov/pubmed/36722959
http://dx.doi.org/10.1128/spectrum.05270-22