Limited sampling strategies for individualized BAX 855 prophylaxis in severe hemophilia A: in silico evaluation

Limited sampling strategies (LSS) lower the burden of pharmacokinetic (PK)-guided dosing, but an extensive evaluation of LSS for BAX 855 (Adynovi) is currently lacking. This study aimed to develop a LSS for BAX 855 and combine this with a LSS of a standard half-life (SHL) factor VIII (FVIII) concent...

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Detalles Bibliográficos
Autores principales: Bukkems, Laura H., Goedhart, Tine M.H.J., Zwaan, C. Michel, Cnossen, Marjon H., Mathôt, Ron A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101132/
https://www.ncbi.nlm.nih.gov/pubmed/37038844
http://dx.doi.org/10.1097/MBC.0000000000001204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101132/
https://www.ncbi.nlm.nih.gov/pubmed/37038844
http://dx.doi.org/10.1097/MBC.0000000000001204

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