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HDAC6 Triggers the ATM-Dependent DNA Damage Response To Promote PRV Replication

Pseudorabies virus (PRV) infection is modulated by various cellular host factors. In this study, we investigated the role of histone deacetylase 6 (HDAC6) in this process. We determined HDAC6 expression in vitro and performed gene knockout, pharmacological inhibition analyses, immunofluorescence ass...

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Detalles Bibliográficos
Autores principales: Xu, Weiyin, Yan, Ping, Zhou, Ziyan, Yao, Jingting, Pan, Haochun, Jiang, Luyao, Bo, Zongyi, Ni, Bo, Sun, Mingxia, Gao, Song, Huan, Changchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101138/
https://www.ncbi.nlm.nih.gov/pubmed/36951571
http://dx.doi.org/10.1128/spectrum.02132-22