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Bioinformatic analysis predicts that ethanol exposure during early development causes alternative splicing alterations of genes involved in RNA post-transcriptional regulation

Prenatal ethanol exposure is associated with neurodevelopmental defects and long-lasting cognitive deficits, which are grouped as fetal alcohol spectrum disorders (FASD). The molecular mechanisms underlying FASD are incompletely characterized. Alternative splicing, including the insertion of microex...

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Detalles Bibliográficos
Autores principales: Fuentes-Beals, Camilo, Olivares-Costa, Montserrat, Andrés, María Estela, Haeger, Paola A., Riadi, Gonzalo, Oliva, Carlos, Faunes, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101408/
https://www.ncbi.nlm.nih.gov/pubmed/37053190
http://dx.doi.org/10.1371/journal.pone.0284357