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In vivo detection of substantia nigra and locus coeruleus volume loss in Parkinson’s disease using neuromelanin-sensitive MRI: Replication in two cohorts

Patients with Parkinson’s disease undergo a loss of melanized neurons in substantia nigra pars compacta and locus coeruleus. Very few studies have assessed substantia nigra pars compacta and locus coeruleus pathology in Parkinson’s disease simultaneously with magnetic resonance imaging (MRI). Neurom...

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Detalles Bibliográficos
Autores principales: Hwang, Kristy S., Langley, Jason, Tripathi, Richa, Hu, Xiaoping P., Huddleston, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101455/
https://www.ncbi.nlm.nih.gov/pubmed/37053195
http://dx.doi.org/10.1371/journal.pone.0282684