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Variation in anthelmintic responses are driven by genetic differences among diverse C. elegans wild strains

Treatment of parasitic nematode infections in humans and livestock relies on a limited arsenal of anthelmintic drugs that have historically reduced parasite burdens. However, anthelmintic resistance (AR) is increasing, and little is known about the molecular and genetic causes of resistance for most...

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Detalles Bibliográficos
Autores principales: Shaver, Amanda O., Wit, Janneke, Dilks, Clayton M., Crombie, Timothy A., Li, Hanchen, Aroian, Raffi V., Andersen, Erik C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101645/
https://www.ncbi.nlm.nih.gov/pubmed/37011090
http://dx.doi.org/10.1371/journal.ppat.1011285