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Exogenous Hydrogen Sulfide Activates PI3K/Akt/eNOS Pathway to Improve Replicative Senescence in Human Umbilical Vein Endothelial Cells

BACKGROUND: Endothelial cell senescence is one of the key mechanistic factors in the pathogenesis of atherosclerosis. In terms of molecules, the phosphatidylinositol 3-kinase/protein kinase B/endothelial nitric oxide synthase (PI3K/Akt/eNOS) signaling plays an important role in the prevention and co...

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Detalles Bibliográficos
Autores principales: Niu, Haiming, Li, Jianwei, Liang, Hongkai, Wu, Guishen, Chen, Miaolian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101749/
https://www.ncbi.nlm.nih.gov/pubmed/37064727
http://dx.doi.org/10.1155/2023/7296874