Aldehyde Dehydrogenase 2 Ameliorates LPS-Induced Acute Kidney Injury through Detoxification of 4-HNE and Suppression of the MAPK Pathway

Lipopolysaccharide (LPS)-induced septic acute kidney injury (AKI) is determined as a devastating organ dysfunction elicited by an inappropriate response to infection with high morbidity and mortality rates. Previous evidence has illustrated an indispensable role of mitochondrial aldehyde dehydrogena...

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Detalles Bibliográficos
Autores principales: Jin, Jifu, Chang, Rebecca Suchi, Xu, Sujuan, Xia, Guang, Wong, Jennifer Ming Jen, Fang, Yi, Jia, Ping, Ding, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101750/
https://www.ncbi.nlm.nih.gov/pubmed/37064008
http://dx.doi.org/10.1155/2023/5513507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101750/
https://www.ncbi.nlm.nih.gov/pubmed/37064008
http://dx.doi.org/10.1155/2023/5513507

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