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Aldehyde Dehydrogenase 2 Ameliorates LPS-Induced Acute Kidney Injury through Detoxification of 4-HNE and Suppression of the MAPK Pathway
Lipopolysaccharide (LPS)-induced septic acute kidney injury (AKI) is determined as a devastating organ dysfunction elicited by an inappropriate response to infection with high morbidity and mortality rates. Previous evidence has illustrated an indispensable role of mitochondrial aldehyde dehydrogena...
Autores principales: | Jin, Jifu, Chang, Rebecca Suchi, Xu, Sujuan, Xia, Guang, Wong, Jennifer Ming Jen, Fang, Yi, Jia, Ping, Ding, Xiaoqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101750/ https://www.ncbi.nlm.nih.gov/pubmed/37064008 http://dx.doi.org/10.1155/2023/5513507 |
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