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MALAT1 Mediates α-Synuclein Expression through miR-23b-3p to Induce Autophagic Impairment and the Inflammatory Response in Microglia to Promote Apoptosis in Dopaminergic Neuronal Cells

BACKGROUND: Parkinson's disease (PD) is a very common neurodegenerative disease that adversely affects the physical and mental health of many patients, but there is currently no effective treatment. OBJECTIVE: To this end, this study focused on investigating the potential mechanisms leading to...

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Detalles Bibliográficos
Autores principales: Geng, Xin, Zou, Yanghong, Li, Shipeng, Qi, Renli, Yu, Hualin, Li, Jinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101752/
https://www.ncbi.nlm.nih.gov/pubmed/37064502
http://dx.doi.org/10.1155/2023/4477492