Acetylation of histone H2B marks active enhancers and predicts CBP/p300 target genes

Chromatin features are widely used for genome-scale mapping of enhancers. However, discriminating active enhancers from other cis-regulatory elements, predicting enhancer strength and identifying their target genes is challenging. Here we establish histone H2B N-terminus multisite lysine acetylation...

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Detalles Bibliográficos
Autores principales: Narita, Takeo, Higashijima, Yoshiki, Kilic, Sinan, Liebner, Tim, Walter, Jonas, Choudhary, Chunaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101849/
https://www.ncbi.nlm.nih.gov/pubmed/37024579
http://dx.doi.org/10.1038/s41588-023-01348-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101849/
https://www.ncbi.nlm.nih.gov/pubmed/37024579
http://dx.doi.org/10.1038/s41588-023-01348-4

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