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Acetylation of histone H2B marks active enhancers and predicts CBP/p300 target genes
Chromatin features are widely used for genome-scale mapping of enhancers. However, discriminating active enhancers from other cis-regulatory elements, predicting enhancer strength and identifying their target genes is challenging. Here we establish histone H2B N-terminus multisite lysine acetylation...
Autores principales: | Narita, Takeo, Higashijima, Yoshiki, Kilic, Sinan, Liebner, Tim, Walter, Jonas, Choudhary, Chunaram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101849/ https://www.ncbi.nlm.nih.gov/pubmed/37024579 http://dx.doi.org/10.1038/s41588-023-01348-4 |
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