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Bipotent transitional liver progenitor cells contribute to liver regeneration

Following severe liver injury, when hepatocyte-mediated regeneration is impaired, biliary epithelial cells (BECs) can transdifferentiate into functional hepatocytes. However, the subset of BECs with such facultative tissue stem cell potential, as well as the mechanisms enabling transdifferentiation,...

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Detalles Bibliográficos
Autores principales: Pu, Wenjuan, Zhu, Huan, Zhang, Mingjun, Pikiolek, Monika, Ercan, Caner, Li, Jie, Huang, Xiuzhen, Han, Ximeng, Zhang, Zhenqian, Lv, Zan, Li, Yan, Liu, Kuo, He, Lingjuan, Liu, Xiuxiu, Heim, Markus H., Terracciano, Luigi M., Tchorz, Jan S., Zhou, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101857/
https://www.ncbi.nlm.nih.gov/pubmed/36914834
http://dx.doi.org/10.1038/s41588-023-01335-9