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Label-free, multi-parametric assessments of cell metabolism and matrix remodeling within human and early-stage murine osteoarthritic articular cartilage

Osteoarthritis (OA) is characterized by the progressive deterioration of articular cartilage, involving complicated cell-matrix interactions. Systematic investigations of dynamic cellular and matrix changes during OA progression are lacking. In this study, we use label-free two-photon excited fluore...

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Detalles Bibliográficos
Autores principales: Liu, Zhiyi, Hui Mingalone, Carrie K., Gnanatheepam, Einstein, Hollander, Judith M., Zhang, Yang, Meng, Jia, Zeng, Li, Georgakoudi, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102009/
https://www.ncbi.nlm.nih.gov/pubmed/37055483
http://dx.doi.org/10.1038/s42003-023-04738-w