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Synthesis of vancomycin fluorescent probes that retain antimicrobial activity, identify Gram-positive bacteria, and detect Gram-negative outer membrane damage

Antimicrobial resistance is an urgent threat to human health, and new antibacterial drugs are desperately needed, as are research tools to aid in their discovery and development. Vancomycin is a glycopeptide antibiotic that is widely used for the treatment of Gram-positive infections, such as life-t...

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Detalles Bibliográficos
Autores principales: Zhang, Bing, Phetsang, Wanida, Stone, M. Rhia L., Kc, Sanjaya, Butler, Mark S., Cooper, Matthew A., Elliott, Alysha G., Łapińska, Urszula, Voliotis, Margaritis, Tsaneva-Atanasova, Krasimira, Pagliara, Stefano, Blaskovich, Mark A. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102067/
https://www.ncbi.nlm.nih.gov/pubmed/37055536
http://dx.doi.org/10.1038/s42003-023-04745-x