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Profiling target engagement and cellular uptake of cRGD-decorated clinical-stage core-crosslinked polymeric micelles

Polymeric micelles are increasingly explored for tumor-targeted drug delivery. CriPec® technology enables the generation of core‐crosslinked polymeric micelles (CCPMs) based on thermosensitive (mPEG-b-pHPMAmLac(n)) block copolymers, with high drug loading capacity, tailorable size, and controlled dr...

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Detalles Bibliográficos
Autores principales: De Lorenzi, Federica, Rizzo, Larissa Yokota, Daware, Rasika, Motta, Alessandro, Baues, Maike, Bartneck, Matthias, Vogt, Michael, van Zandvoort, Marc, Kaps, Leonard, Hu, Qizhi, Thewissen, Marielle, Casettari, Luca, Rijcken, Cristianne J. F., Kiessling, Fabian, Sofias, Alexandros Marios, Lammers, Twan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102119/
https://www.ncbi.nlm.nih.gov/pubmed/35816231
http://dx.doi.org/10.1007/s13346-022-01204-8