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Profiling target engagement and cellular uptake of cRGD-decorated clinical-stage core-crosslinked polymeric micelles
Polymeric micelles are increasingly explored for tumor-targeted drug delivery. CriPec® technology enables the generation of core‐crosslinked polymeric micelles (CCPMs) based on thermosensitive (mPEG-b-pHPMAmLac(n)) block copolymers, with high drug loading capacity, tailorable size, and controlled dr...
Autores principales: | De Lorenzi, Federica, Rizzo, Larissa Yokota, Daware, Rasika, Motta, Alessandro, Baues, Maike, Bartneck, Matthias, Vogt, Michael, van Zandvoort, Marc, Kaps, Leonard, Hu, Qizhi, Thewissen, Marielle, Casettari, Luca, Rijcken, Cristianne J. F., Kiessling, Fabian, Sofias, Alexandros Marios, Lammers, Twan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102119/ https://www.ncbi.nlm.nih.gov/pubmed/35816231 http://dx.doi.org/10.1007/s13346-022-01204-8 |
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