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Ripply suppresses Tbx6 to induce dynamic-to-static conversion in somite segmentation

The metameric pattern of somites is created based on oscillatory expression of clock genes in presomitic mesoderm. However, the mechanism for converting the dynamic oscillation to a static pattern of somites is still unclear. Here, we provide evidence that Ripply/Tbx6 machinery is a key regulator of...

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Detalles Bibliográficos
Autores principales: Yabe, Taijiro, Uriu, Koichiro, Takada, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102234/
https://www.ncbi.nlm.nih.gov/pubmed/37055428
http://dx.doi.org/10.1038/s41467-023-37745-w