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Obesity, but not high-fat diet, is associated with bone loss that is reversed via CD4(+)CD25(+)Foxp3(+) Tregs-mediated gut microbiome of non-obese mice

Osteoporosis is characterized by decreased bone mass, microarchitectural deterioration, and increased bone fragility. High-fat diet (HFD)-induced obesity also results in bone loss, which is associated with an imbalanced gut microbiome. However, whether HFD-induced obesity or HFD itself promotes oste...

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Detalles Bibliográficos
Autores principales: Song, Wei, Sheng, Qinglin, Bai, Yuying, Li, Li, Ning, Xin, Liu, Yangeng, Song, Chen, Wang, Tianyi, Dong, Xiaohua, Luo, Yane, Hu, Jinhong, Zhu, Lina, Cui, Xiaole, Chen, Bing, Li, Lingling, Cai, Congli, Cui, Haobo, Yue, Tianli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102288/
https://www.ncbi.nlm.nih.gov/pubmed/37055440
http://dx.doi.org/10.1038/s41538-023-00190-6