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Obesity, but not high-fat diet, is associated with bone loss that is reversed via CD4(+)CD25(+)Foxp3(+) Tregs-mediated gut microbiome of non-obese mice
Osteoporosis is characterized by decreased bone mass, microarchitectural deterioration, and increased bone fragility. High-fat diet (HFD)-induced obesity also results in bone loss, which is associated with an imbalanced gut microbiome. However, whether HFD-induced obesity or HFD itself promotes oste...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102288/ https://www.ncbi.nlm.nih.gov/pubmed/37055440 http://dx.doi.org/10.1038/s41538-023-00190-6 |