Rational strategies for enhancing mAb binding to SARS-CoV-2 variants through CDR diversification and antibody-escape prediction

Since the emergence of SARS-CoV-2, dozens of variants of interest and half a dozen variants of concern (VOCs) have been documented by the World Health Organization. The emergence of these VOCs due to the continuous evolution of the virus is a major concern for COVID-19 therapeutic antibodies and vac...

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Detalles Bibliográficos
Autores principales: Shah, Masaud, Shin, Ji-Yon, Woo, Hyun Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102385/
https://www.ncbi.nlm.nih.gov/pubmed/37063859
http://dx.doi.org/10.3389/fimmu.2023.1113175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102385/
https://www.ncbi.nlm.nih.gov/pubmed/37063859
http://dx.doi.org/10.3389/fimmu.2023.1113175

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