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Cationic lipid-assisted nanoparticles for simultaneous delivery of CD47 siRNA and R848 to promote antitumor immune responses

Introduction: Triple-negative breast cancer (TNBC) usually has a poor prognosis. Although the immunotherapy of TNBC has achieved great progress, only a few patients can benefit from the current treatment. CD47 is widely expressed on the surface of TNBC cells and may become an immune checkpoint for T...

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Detalles Bibliográficos
Autores principales: Li, Simin, Chen, Yichang, Ma, Ruolin, Du, Ye, Han, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102467/
https://www.ncbi.nlm.nih.gov/pubmed/37063284
http://dx.doi.org/10.3389/fphar.2023.1142374