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Rev-erbα agonist SR9009 protects against cerebral ischemic injury through mechanisms involving Nrf2 pathway

Backgrounds: The circadian clock protein Rev-erbα is a crucial regulator of circadian rhythms that affects multiple molecular, cellular, and physiology pathways that control susceptibility, injury, and recovery in the neurological disorders. Emerging evidence suggest that Rev-erbα plays a key role i...

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Detalles Bibliográficos
Autores principales: Sheng, Mingyue, Chen, Xun, Yu, Yan, Wu, Qi, Kou, Junping, Chen, Gangling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102520/
https://www.ncbi.nlm.nih.gov/pubmed/37063298
http://dx.doi.org/10.3389/fphar.2023.1102567