pOpsicle: An all-optical reporter system for synaptic vesicle recycling combining pH-sensitive fluorescent proteins with optogenetic manipulation of neuronal activity

pH-sensitive fluorescent proteins are widely used to study synaptic vesicle (SV) fusion and recycling. When targeted to the lumen of SVs, fluorescence of these proteins is quenched by the acidic pH. Following SV fusion, they are exposed to extracellular neutral pH, resulting in a fluorescence increa...

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Detalles Bibliográficos
Autores principales: Seidenthal, Marius, Jánosi, Barbara, Rosenkranz, Nils, Schuh, Noah, Elvers, Nora, Willoughby, Miles, Zhao, Xinda, Gottschalk, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102542/
https://www.ncbi.nlm.nih.gov/pubmed/37066081
http://dx.doi.org/10.3389/fncel.2023.1120651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102542/
https://www.ncbi.nlm.nih.gov/pubmed/37066081
http://dx.doi.org/10.3389/fncel.2023.1120651

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