Characterization of a novel tetravalent botulism antitoxin based on receptor-binding domain of BoNTs

ABSTRACT: Botulinum neurotoxin (BoNTs; serotypes A, B, E, and F) cause botulism disease in humans, which could be effectively treated using antitoxins. Herein, we established a novel receptor-binding domain (RBD)-based antitoxin using recombinant C terminal heavy chain (Hc) domains of BoNTs as immun...

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Detalles Bibliográficos
Autores principales: Shi, Dan-Yang, Lu, Jian-Sheng, Mao, Yun-Yun, Liu, Fu-Jia, Wang, Rong, Du, Peng, Yu, Shuo, Yu, Yun-Zhou, Yang, Zhi-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Biotechnological Products and Process Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102682/
https://www.ncbi.nlm.nih.gov/pubmed/37058230
http://dx.doi.org/10.1007/s00253-023-12515-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102682/
https://www.ncbi.nlm.nih.gov/pubmed/37058230
http://dx.doi.org/10.1007/s00253-023-12515-2

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