Cell-Free Urine and Plasma DNA Mutational Analysis Predicts Neoadjuvant Chemotherapy Response and Outcome in Patients with Muscle-Invasive Bladder Cancer

PURPOSE: To investigate the use of plasma and urine DNA mutation analysis for predicting neoadjuvant chemotherapy (NAC) response and oncological outcome in patients with muscle-invasive bladder cancer. EXPERIMENTAL DESIGN: Whole-exome sequencing of tumor and germline DNA was performed for 92 patient...

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Detalles Bibliográficos
Autores principales: Christensen, Emil, Nordentoft, Iver, Birkenkamp-Demtröder, Karin, Elbæk, Sara K., Lindskrog, Sia V., Taber, Ann, Andreasen, Tine G., Strandgaard, Trine, Knudsen, Michael, Lamy, Philippe, Agerbæk, Mads, Jensen, Jørgen B., Dyrskjøt, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102843/
https://www.ncbi.nlm.nih.gov/pubmed/36780195
http://dx.doi.org/10.1158/1078-0432.CCR-22-3250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102843/
https://www.ncbi.nlm.nih.gov/pubmed/36780195
http://dx.doi.org/10.1158/1078-0432.CCR-22-3250

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