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G-Quadruplex Structures Are Key Modulators of Somatic Structural Variants in Cancers
G-quadruplexes (G4) are noncanonical secondary genome structures. Aberrant formation of G4s can impair genome integrity. Investigation of the relationship between G4s and somatic structural variants (SV) in cancers could provide a better understanding of the role of G4 formation in cancer developmen...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102852/ https://www.ncbi.nlm.nih.gov/pubmed/36791413 http://dx.doi.org/10.1158/0008-5472.CAN-22-3089 |