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G-Quadruplex Structures Are Key Modulators of Somatic Structural Variants in Cancers

G-quadruplexes (G4) are noncanonical secondary genome structures. Aberrant formation of G4s can impair genome integrity. Investigation of the relationship between G4s and somatic structural variants (SV) in cancers could provide a better understanding of the role of G4 formation in cancer developmen...

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Detalles Bibliográficos
Autores principales: Zhang, Rongxin, Shu, Huiling, Wang, Yuqi, Tao, Tiantong, Tu, Jing, Wang, Cheng, Mergny, Jean-Louis, Sun, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102852/
https://www.ncbi.nlm.nih.gov/pubmed/36791413
http://dx.doi.org/10.1158/0008-5472.CAN-22-3089