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Bayesian Machine Learning Enables Identification of Transcriptional Network Disruptions Associated with Drug-Resistant Prostate Cancer

Survival rates of patients with metastatic castration-resistant prostate cancer (mCRPC) are low due to lack of response or acquired resistance to available therapies, such as abiraterone (Abi). A better understanding of the underlying molecular mechanisms is needed to identify effective targets to o...

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Detalles Bibliográficos
Autores principales: Blatti, Charles, de la Fuente, Jesús, Gao, Huanyao, Marín-Goñi, Irene, Chen, Zikun, Zhao, Sihai D., Tan, Winston, Weinshilboum, Richard, Kalari, Krishna R., Wang, Liewei, Hernaez, Mikel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102853/
https://www.ncbi.nlm.nih.gov/pubmed/36779846
http://dx.doi.org/10.1158/0008-5472.CAN-22-1910