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Developing a predictive signature for two trial endpoints using the cross-validated risk scores method
The existing cross-validated risk scores (CVRS) design has been proposed for developing and testing the efficacy of a treatment in a high-efficacy patient group (the sensitive group) using high-dimensional data (such as genetic data). The design is based on computing a risk score for each patient an...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102911/ https://www.ncbi.nlm.nih.gov/pubmed/34165151 http://dx.doi.org/10.1093/biostatistics/kxaa055 |