Secreted factors induced by PKC modulators do not indirectly cause HIV latency reversal

HIV can establish a long-lived latent infection in cells harboring integrated non-expressing proviruses. Latency reversing agents (LRAs), including protein kinase C (PKC) modulators, can induce expression of latent HIV, thereby reducing the latent reservoir in animal models. However, PKC modulators...

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Detalles Bibliográficos
Autores principales: Moran, Jose A., Ranjan, Alok, Hourani, Rami, Kim, Jocelyn T., Wender, Paul A., Zack, Jerome A., Marsden, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103183/
https://www.ncbi.nlm.nih.gov/pubmed/36842270
http://dx.doi.org/10.1016/j.virol.2023.02.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103183/
https://www.ncbi.nlm.nih.gov/pubmed/36842270
http://dx.doi.org/10.1016/j.virol.2023.02.009

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