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Secreted factors induced by PKC modulators do not indirectly cause HIV latency reversal
HIV can establish a long-lived latent infection in cells harboring integrated non-expressing proviruses. Latency reversing agents (LRAs), including protein kinase C (PKC) modulators, can induce expression of latent HIV, thereby reducing the latent reservoir in animal models. However, PKC modulators...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103183/ https://www.ncbi.nlm.nih.gov/pubmed/36842270 http://dx.doi.org/10.1016/j.virol.2023.02.009 |