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Urine Complement Factor Ba Is Associated with AKI in Critically Ill Children

KEY POINTS: Complement activation, specifically factor B, is implicated in AKI pathogenesis in animal models. Urine Ba (an activation fragment of factor B) was significantly higher in critically ill children with stage 3 AKI and sepsis-AKI. If larger studies show similar association between urine Ba...

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Detalles Bibliográficos
Autores principales: Stenson, Erin K., Edelstein, Charles L., You, Zhiying, Miyazaki-Anzai, Shinobu, Thurman, Joshua M., Dixon, Bradley P., Zappitelli, Michael, Goldstein, Stuart L., Akcan Arikan, Ayse, Kendrick, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Nephrology 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103361/
https://www.ncbi.nlm.nih.gov/pubmed/36758197
http://dx.doi.org/10.34067/KID.0000000000000077